High-Throughput Clinical Input
The workflow begins with a routine, minimally invasive blood draw. NeXendia’s high-sensitivity platform requires less than 150 µL of plasma.
This ultra-low volume allows seamless integration into clinical trial protocols and serial, longitudinal patient monitoring.
RNA-Protein Complex Capture
Naked cell-free RNA degrades rapidly in biofluids, introducing massive noise. We focus instead on capturing **cell-free RNA-protein complexes**.
By selectively capturing intact, protein-protected RNA cargo, we preserve the biological signal that others throw away.
Multi-Dimensional Mapping
Once captured, we map the enriched complexes across three critical biological domains, profiling the cellular state of target organs:
Fragmentomics ML Engine
The sequenced profiles are processed through our proprietary machine learning deconvolution models.
By filtering out over 90% of background noise, our algorithms resolve complex RNA fragmentation footprints into precise, tissue-specific biological signals.
Venture-Scale Platform Applications
Deconvolution translates raw sequence databases into quantitative proof of target engagement and safety.
We validate the platform via high-value biopharma drug co-development, while building a proprietary diagnostic atlas for early disease detection.
